The Overseas Investors Chamber of Commerce and Industry stemmed from and superceded the Karachi Chamber Of Commerce, which was founded in 1860 it is the oldest Chamber of Commerce in Pakistan. To conform with the government policy of rationalization and to prevent, proliferation of trade bodies, the present name of the Chamber Overseas Investors Chamber of Commerce and Industry in the year 1968.

The Chamber has 168 members of which 11 are industrial undertakings , 14 in Banking companies, 16 in Chemicals/pesticides/fertilizers, 18 in Engineering & industrial products, 12 in Finance & leasing companies, 14 in Food & consumer products, 3 in Information technology, 3 in Insurance, 28 in Oil/gas & energy, 24 in Pharmaceutical industries, 27 in Shipping, airlines, trading & other services, 9 in Tobacco & other manufacturing companies. It is a mix of large and small international enterprises participating in all sectors of the economy, The following countries are represented.